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Membrane compartment of Can1 (MCC): specialized functional microdomain of the yeast plasma membrane
Doudová, Lenka ; Malínský, Jan (advisor) ; Vopálenská, Irena (referee)
Membrane compartment of Can1 (MCC): specialized functional microdomain of the yeast plasma membrane Yeast plasma membrane is divided into several different compartments. Membrane compartment of Can1 is specific for its protein and lipid composition, furthermore it creates furrow-like invaginations on the plasma membrane. These invaginations are made by multiprotein complexes called eisosomes, which are located in the cytosolic side of MCCs. It was established that this domain plays an important role in response to various environmental stresses. Sur7 and Nce102 are transmembrane MCC proteins of unknown function. Sur7 is most likely a structural protein within MCC, Nce102 is probably important in regulation of kinases associated with MCC/eisosomes. Key words: biological membrane, membrane microdomains, eisosome, S. cerevisiae, Sur7, Nce102

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